Badanie nad terapią MSV/AS u pacjentów z przewlekłym bólem krzyża spowodowanym zwyrodnieniową chorobą krążka międzykręgowego, nieodpowiadających na konwencjonalne leczenie

Chronic low back pain is a common issue that can be caused by a condition known as Degenerative Disc Disease. This condition occurs when the discs in the spine, which act as cushions between the bones, start to break down. This study is looking at a new treatment for people with this type of back pain that hasn't improved with usual treatments. The treatment being tested involves using special cells called MSV Allogenic bone marrow stromal mesenchymal cells. These cells are injected directly into the affected area of the spine.

The purpose of the study is to see if this cell therapy can help reduce pain and improve the function of the spine in people with Degenerative Disc Disease. The study will compare the effects of the cell therapy to a placebo, which is a treatment that looks like the real one but doesn't have any active ingredients. Participants will receive either the cell therapy or the placebo and will be monitored over a period of 12 months to see how their pain and spine function change.

Throughout the study, participants will have their pain levels measured using a scale called the visual analog scale (VAS), and their ability to perform daily activities will be assessed using the Oswestry disability index (ODI). Additionally, the study will use MRI scans to check if the fluid content in the discs has improved. The goal is to determine if the cell therapy can provide significant relief from pain and improve the quality of life for those suffering from chronic low back pain due to Degenerative Disc Disease.